On quantitative assessment of microbe risk caused by exposure to enteric viruses in drinking water

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UDC: 
613, 614, 616.9
DOI: 
10.21668/health.risk/2019.2.12.eng
Authors: 

E.V.Baydakova1,2, T.N. Unguryanu1,2, R.I. Mikhailova3

Organization: 

1Arkhangelsk Region Department of the Federal Service on Customers' Rights Protection and Human Well-Being Surveillance, 24 Gaidar St., Arkhangelsk, 163000, Russian Federation
2Northern State Medical University, 51 Troitsky Av., Arkhangelsk, 163000, Russian Federation
3Centre for Strategic Planning and Management of Biomedical Health Risks, Russian Ministry of Health, Bldg. 1, 10 Pogodinskaya Sr., Moscow, 119121, Russian Federation

Abstract: 

The authors assessed microbiological risks of acute intestinal infections (AII) with viral etiology caused by drinking water taken from centralized water supply systems among overall urban population in Arkhangelsk region over 2006-2017. The re-search was performed with Quantitative Microbial Risk Assessment (QMRA) procedure. It was revealed that acute intestinal viral infections prevailed among intestinal infections; the most widely spread ones were rotavirus infection (86.9%), norovirus infection (7.7%), and enterovirus infection (3.7%). The authors also performed comparative analysis of spatial distribution and long-term dynamics of incidence with AII which were possibly caused by infectious agents entering a body with water. The analysis revealed that rotavirus and norovirus infections frequently occurred in Arkhangelsk, Novodvinsk, Koryazhma, and Kotlas. Incidence with rotavirus infection among population in Koryazhma and Arkhangelsk grew 1.5-1.6 times faster than epidemiological processes on the reference territory. Coliphages contents were equal to Р95in drinking water taken from centralized water supply systems in Arkhangelsk and Koryazhma, and it was 1.4 and 2.2 times higher respectively than the hygienic standard. Rotavirus, norovirus, and enterovirus infections were highly likely to occur in Arkhangelsk (R=0.97-0.99), and rotavirus infection, in Koryazhma (R=0.95). Average probability of norovirus infection (R=0.58) and enterovirus infection (R=0.43) was detected in Koryazhma. The research results indicate that Quantitative Microbial Risk Assessment (QMRA) procedure is feasible and significant within the system of sanitary-epidemiologic surveillance over water treatment; it substantiates the necessity to create and implement virology monitoring over centralized drinking water supply.

Keywords: 
drinking water, water supply, acute intestinal infections, viral infections, coliphages contents, risk assessment, microbiological risk, QMRA
Baydakova E.V., Unguryanu T.N., Mikhaylova R.I. On quantitative assessment of microbe risk caused by exposure to enteric viruses in drinking water. Health Risk Analysis, 2019, no. 2, pp. 108–114. DOI: 10.21668/health.risk/2019.2.12.eng
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Received: 
27.03.2019
Accepted: 
20.05.2019
Published: 
30.06.2019

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