Modern chemical factors’ risk and impact management international requirements and their implementation in the system of state sanitary-epidemiologic control

The analysis performed of modern trends in chemicals handling and implementation in the RF and abroad showed the understanding that the chemical factor poses an integral hazard to human health and the environment and requires significant conjoint efforts to regulate it as well as the necessity to harmonize domestic regulatory and methodological bases with international requirements; to implement GLP and GHS into the hygiene and preventive toxicology practice ; to create and implement a national program in systemic investigations into substances publicly traded on the market in order to withdraw those posing a high risk from circulation and replace them by safer alternatives.