Calculation of supplementary morbidity and mortality through evolutionary modeling of public health risk

View or download the full article: 
UDC: 
51-76, 613
Authors: 

D.A. Kiryanov, M.R. Kamaltdinov

Organization: 

FBSI “Federal Scientific Center for Medical and Preventive Health Risk Management Technologies”, Perm, 614045, Russia

Abstract: 

The algorithm of population quantitative estimates for additional morbidity and mortality, corresponding to the risk of disorders of the relevant functions of organs and systems of the human body, has been developed based on an evolutionary model. At each stage of the algorithm the necessary data sources, methods of treatment and intermediate results are described in detail, the method takes into account the peculiarities of age distribution of health indicators using Severity Index. Testing of the method is performed on the example of the complex influence of diverse environmental factors on several critical organs and systems. The calculation results show that the additional risk of morbidity and mortality due to diseases of almost all classes and systems increases with age, taking the invalid values in the above working age. In addition, the structure of the additional risks demonstrates overbalance of conditions associated with disorders of blood
circulatory system. The results of risk assessment according to the proposed algorithms can serve as a basis for additional studies of environmental factors impacting on health, organization of health prevention and control and
monitoring events.

Keywords: 
assessment of additional morbidity and mortality, evolutional modeling, risk of disorder of functions of organs and systems
Kiryanov D.A., Kamaltdinov M.R.Calculation of supplementary morbidity and mortality through evolutionary modeling of public health risk. Health Risk Analysis, 2014, no. 1, pp. 31-39
References: 
  1. Zaytseva N.V., Shur P.Z. Aktual'nye voprosy metodicheskoy podderzhki otsenki riska dlya zdorov'ya nase-leniya pri obespechenii bezopasnosti produktsii: mirovoy zarubezhnyy opyt i praktika tamozhennogo soyuza [Topi-cal issues of methodological support of public health risk assessment while ensuring the safety of products: global foreign experience and practice of the customs union]. Analiz riska zdorov'yu, 2013, no. 4, pp. 4–16.
  2. Zaytseva N.V., Shur P.Z., Aminova A.I., Kir'yanov D.A., Kamaltdinov M.R. K otsenke dopolnitel'nogo riska zabolevaniy zheludochno-kishechnogo trakta, assotsiirovannykh s disbiozom kishechnoy mikroflory vsledstvie vozdeystviya ostatochnykh kontsentratsiy tetratsiklina v pishchevykh produktakh [Assessing the addi-tional risk of diseases of the gastrointestinal tract associated with dysbiosis of intestinal microflora due to the im-pact of tetracycline residues in foods]. Zdorov'e naseleniya i sreda obitaniya,  2012, no. 7, pp. 46–48.
  3. Zaytseva N.V., Shur P.Z., Kir'yanov D.A., Alekseev V.B., Sboev A.S., Volk-Leonovich O.P. Kolichest-vennaya otsenka nekantserogennogo riska dlya zdorov'ya naseleniya [Quantitative assessment of non-cancer risk to public health]. Gigiena i sanitariya, 2008, no. 6, pp. 64–67.
  4. Trusov P.V., Zaytseva N.V., Kir'yanov D.A., Kamaltdinov M.R., Tsinker M.Yu., Chigvintsev V.M., Lanin D.V. Matematicheskaya model' evolyutsii funktsional'nykh narusheniy v organizme cheloveka s uchetom vneshnes-redovykh faktorov [Mathematical model for the evolution of functional disorders in the human body taking into account environmental factors]. Matematicheskaya biologiya i bioinformatika, 2012, no. 2, pp. 589–610, avaible at: http: //www.matbio.org/2012/Trusov_7_589.pdf.
  5. Zaytseva N.V., Shur P.Z., May I.V., Kir'yanov D.A. Metodicheskie podkhody k otsenke integral'nogo riska zdorov'yu naseleniya na osnove evolyutsionnykh matematicheskikh modeley [Methodological approaches to the assessment of the integral health risk on the basis of mathematical models of evolution]. Zdorov'e naseleniya i sreda obitaniya, 2011, no. 10, pp. 6–9.
  6. Zaytseva N.V., Shur P.Z., Kir'yanov D.A., Kamaltdinov M.R., Tsinker M.Yu.Metodicheskie podkhody k otsenke populyatsionnogo riska zdorov'yu na osnove evolyutsionnykh modeley [Methodological approaches to the assessment of population health risk on the basis of evolutionary models]. Zdorov'e naseleniya i sreda obitaniya, 2013, no. 1 (238), pp. 4–6.
  7. Zaytseva N.V., Trusov P.V., Shur P.Z., Kir'yanov D.A., Chigvintsev V.M., Tsinker M.Yu. Metodicheskie podkhody k otsenke riska vozdeystviya raznorodnykh faktorov sredy obitaniya na zdorov'e naseleniya na osnove evolyutsionnykh modeley [Methodological approaches to the assessment of risk of exposure to diverse environ-mental factors on human health based on evolutionary models]. Analiz riska zdorov'yu, 2013, no. 1, pp. 15–23.
  8. MR 2.1.10.0062-12. Kolichestvennaya otsenka nekantserogennogo riska pri vozdeystvii khimicheskikh ve-shchestv na osnove postroeniya evolyutsionnykh modeley [MR 2.1.10.0062-12. Quantitative assessment of non-cancer risk with exposure to chemicals on the basis of constructing evolutionary models]. Moscow: Federal'nyy tsentr gigieny i epidemiologii Rospotrebnadzora, 2012. 36 p.
  9. Tsinker M.Yu., Kir'yanov D.A., Kamaltdinov M.R. Primenenie kompleksnogo indeksa narusheniya zdorov'ya naseleniya dlya otsenki populyatsionnogo zdorov'ya v permskom krae [Application of the complex index of health disorders for the assessment of population health in the Perm Krai]. Izvestiya Samarskogo nauchnogo tsentra Rossiyskoy akademii nauk, 2013, vol. 15, no. 3–6, pp. 1988–1992.

You are here