Risk factors able to cause meteorological responses from the immune system in patients with bronchial asthma in sea monsoon climate
L.V. Veremchuk, Т.I. Vitkina
Vladivostok’s branch of Federal governmental budget scientific facility «Far Eastern scientific center of physiology and pathology of breathing» – Scientific research institution of medical climatology and rehabilitation treatment, 73G Russkaya Str., Vladivostok, 690105, Russian Federation
Assessing the characteristics of interseasonal meteorological responses from the immune system remains a controversial scientific problem. The aim of the study was to determine the intensity and nature of the seasonal meteorological responses from the immune system in healthy individuals and patients with bronchial asthma (BA) living in Vladivostok when exposed to favorable and unfavorable weather conditions.
The objects of the study were the immune system indicators and climatic factors selected in a single spatiotemporal aspect. Four hundred and fifty people were examined, of which 160 people were included in the control group and 290 in the group of people with BA. Based on the information-entropy analysis, the seasonal level of meteorological responses was estimated by determining the difference in values (Rconditional – Rwithout %). Using the conditional entropy indicator (Rconditional %) made it possible to estimate the favorable and pathogenic nature of the seasonal impact exerted by climatic factors.
In Vladivostok, weather conditions have the most active effect on the immune system of patients with bronchial asthma, decreasing by 20–30 % from winter to autumn and again sharply increasing by winter, which is the most dangerous period of the year for patients with bronchial asthma. The healthy population of the city has a peak meteorological reaction in winter. Unfavorable and favorable weather conditions are characterized by different levels of impact. In general, the climate in Vladivostok has a predominantly pathogenic orientation for the entire city population. For patients with bronchial asthma, winter and spring are the most unfavorable periods. The immune system of people with bronchial asthma has been shown to actively react to the temperature regime, namely, to low temperatures in winter and to high temperatures with high humidity in summer. By autumn, an increase in health-improving properties of the climate is observed, especially for healthy people.
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