Ambient air quality and risk of circulatory diseases for population of a large city in the European north of Russia
T.N. Rastokina, A.A. Peshkova, T.N. Unguryanu
Northern State Medical University, 51 Troitskii Ave., Arkhangelsk, 163000, Russian Federation
Cardiovascular diseases are the most frequent causes of premature mortality associated with ambient air quality. In the Arkhangelsk region, population mortality caused by diseases of the circulatory system is higher than the national average. The aim of this study was to assess ambient air quality in Arkhangelsk and associated health harm in adult population.
The study relied on using data of ambient air monitoring in Arkhangelsk collected over 2011–2022. We analyzed average annual levels of 23 pollutants and primary incidence of diseases of the circulatory system (CVD) and calculated hazard quotients under chronic inhalation exposure (HQ), hazard index (HI) for the cardiovascular system, and the number of attributable deaths associated with exposure to PM10 and PM2.5.
Over the analyzed period, the average long-term concentrations of most pollutants met hygienic standards. Average levels of formaldehyde, chromium, copper and benzene were found to exceed the MPL by 1.5–2.3 times. Hazard coefficients for formaldehyde (HQ = 2.3), copper (HQ = 1.8) and PM2.5 (HQ = 1.7) were established to be above their permissible value. The risk of developing general toxic effects is determined to be high (HI = 6.6) for the cardiovascular system. The main contribution to the risk level is made by copper and PM2.5. Attributable outcomes of primary cardiovascular incidence among the adult population of Arkhangelsk associated with exposure to PM10 and PM2.5 equaled 10.7 and 2.9 ‰ cases per year. The greatest harm under exposure to PM2.5 is due to the development of coronary artery disease and amounts to 1.9 ‰ cases per year.
- Prüss-Üstün A., Wolf J., Corvalán C., Bos R., Neira M. Preventing disease through healthy environments: a global as-sessment of the burden of disease from environmental risks. Geneva, World Health Organization, 2016, pp. 56–60.
- Li J., Liu F., Liang F., Huang K., Yang X., Xiao Q., Chen J., Liu X. [et al.]. Long-Term Effects of High Exposure to Ambient Fine Particulate Matter on Coronary Heart Disease Incidence: A Population-Based Chinese Cohort Study. Environ. Sci. Technol., 2020. vol. 54, no. 11, pp. 6812–6821. DOI: 10.1021/acs.est.9b06663
- Kim H., Kim J., Kim S., Kang S.-H., Kim H.-J., Kim H., Heo J., Yi S.-M. [et al.]. Cardiovascular Effects of Long-Term Exposure to Air Pollution: A Population-Based Study With 900 845 Person-Years of Follow-up. J. Am. Heart Assoc., 2017, vol. 6, no. 11, pp. e007170. DOI: 10.1161/JAHA.117.007170
- Liang R., Chen R., Yin P., van Donkelaar A., Martin R.V., Burnett R., Cohen A.J., Brauer M. [et al.]. Associations of long-term exposure to fine particulate matter and its constituents with cardiovascular mortality: A prospective cohort study in China. Environ. Int., 2022, vol. 162, pp. 107156. DOI: 10.1016/j.envint.2022.107156
- Xia Y., Liu Z., Hu B., Rangarajan S., Tse L.A., Li Y., Wang J., Hu L. [et al.]. Associations of outdoor fine particulate air pollution and cardiovascular disease: Results from the Prospective Urban and Rural Epidemiology Study in China. Environ. Int., 2023, vol. 174, pp.107829. DOI: 10.1016/j.envint.2023.107829
- Qiu H., Sun S., Tsang H., Wong C.-M., Lee R.S.-Y., Schooling C.M., Tian L. Fine particulate matter exposure and incidence of stroke: A cohort study in Hong Kong. Neurology, 2017, vol. 88, no. 18, pp. 1709–1717. DOI: 10.1212/WNL.0000000000003903
- Liu C., Chen R., Zhao Y., Ma Z., Bi J., Liu Y., Meng X., Wang Y. [et al.]. Associations between ambient fine particu-late air pollution and hypertension: A nationwide cross-sectional study in China. Sci. Total Environ., 2017, vol. 584–585, pp. 869–874. DOI: 10.1016/j.scitotenv.2017.01.133
- Pope C.A. 3rd, Burnett R.T., Thurston G.D., Thun M.J., Calle E.E., Krewski D., Godleski J.J. Cardiovascular mortality and long-term exposure to particulate air pollution: epidemiological evidence of general pathophysiological pathways of disease. Circulation, 2004. vol. 109, no. 1, pp. 71–77. DOI: 10.1161/01.CIR.0000108927.80044.7F
- Zou L., Zong Q., Fu W., Zhang Z., Xu H., Yan S., Mao J., Zhang Y. [et al.]. Long-Term Exposure to Ambient Air Pollution and Myocardial Infarction: A Systematic Review and Meta-Analysis. Front. Med. (Lausanne), 2021, vol. 8, pp. 616355. DOI: 10.3389/fmed.2021.616355
- Lv S., Li Z., Li H., Hu Y., Hu M., Li S., Xie W., Li Y. [et al.]. Long-term effects of particulate matter on incident cardiovascular diseases in middle-aged and elder adults: The CHARLS cohort study. Ecotoxicol. Environ. Saf., 2023, vol. 262, pp. 115181. DOI: 10.1016/j.ecoenv.2023.115181
- Zhang Y., Wang Y., Du Z., Chen S., Qu Y., Hao C., Ju X., Lin Z. [et al.]. Potential causal links between long-term ambient particulate matter exposure and cardiovascular mortality: New evidence from a large community-based cohort in South China. Ecotoxicol. Environ. Saf., 2023, vol. 254, pp. 114730. DOI: 10.1016/j.ecoenv.2023.114730
- Dong G.-H., Qian Z.M., Xaverius P.K., Trevathan E., Maalouf S., Parker J., Yang L., Liu M.-M. [et al.]. Association between long-term air pollution and increased blood pressure and hypertension in China. Hypertension, 2013, vol. 61, no. 3, pp. 578–584. DOI: 10.1161/HYPERTENSIONAHA.111.00003
- Litvinova N.A., Molotilova S.A. The influence of motor transport emissions on morbidity and health risk of the popula-tion of Tyumen city. Ekologiya cheloveka, 2018, vol. 25, no. 8, pp. 11–16. DOI: 10.33396/1728-0869-2018-8-11-16 (in Russian).
- Tsallagova R.B., Kopytenkova O.I., Makoeva F.K. Health risk assessment of population under chronic inhalation ex-posure of automotive transport emissions. Profilakticheskaya i klinicheskaya meditsina, 2021, no. 2 (79), pp. 15–21. DOI: 10.47843/2074-9120_2021_2_15 (in Russian).
- Tafeeva E.A., Ivanov A.V., Titova A.A. Akhmetzyanova I.F. Air pollutions as a risk factor for the population health in Kazan city. Gigiena i sanitariya, 2015, vol. 94, no. 3, pp. 37–40 (in Russian).
- Suchkov V.V., Semaeva E.A. Air pollution risk to health of the population of the cities Samara and Novokuiby-shevsk. Gigiena i sanitariya, 2017, vol. 96, no. 8, pp. 729–733. DOI: 10.47470/0016-9900-2017-96-8-729-733 (in Russian).
- Movchan V., Zubkova P.S., Kalinina I.K., Kuznetsova M.A., Sheinerman N.A. Assessment and forecast of the eco-logical situation in St. Petersburg in terms of air pollution and public health indicators. Vestnik Sankt-Peterburgskogo universiteta. Nauki o Zemle, 2018, vol. 63, no. 2, pp. 178–193. DOI: 10.21638/11701/spbu07.2018.204 (in Russian).
- Chetverkina K.V. Assessing risks of circulatory disorders among adults exposed to ambient air chemical contamination when living in the Perm region. Gigiena i sanitariya, 2020, vol. 99, no. 8, pp. 861–865. DOI: 10.47470/0016-9900-2020-99-8-861-865 (in Russian).
- Kuzmin S.V., Avaliani S.L., Dodina N.S., Shashina T.A., Kislitsin V.A., Sinitsyna O.O. The practice of applying health risk assessment in the Federal Project “Clean Air” in the participating cities (Cherepovets, Lipetsk, Omsk, Novokuznetsk): problems and prospects. Gigiena i sanitariya, 2021, vol. 100, no. 9, pp. 890–896. DOI: 10.47470/0016-9900-2021-100-9-890-896 (in Russian).
- Grigoriev Yu.I., Lyapina N.V. Hygienic evaluation of air quality and health of the child population of Tula. ZNiSO, 2013, no. 8 (245), pp. 29–31 (in Russian).
- Kulyas V.M. Hygienic assessment of non-carcinogenic and carcinogenic risks to the health of the population of the industrial center from aerogenic pollutants. Arkhiv klinicheskoi i eksperimental'noi meditsiny, 2021, vol. 30, no. 1, pp. 55–60 (in Russian).
- Boev V.M., Kryazheva E.A., Kudusova L.Kh., Kryazhev D.A., Perepelkin S.V. Hygienic assessment of ambient air and non-carcinogenic risk for public health living on border territories. ZNiSO, 2019, no. 3 (312), pp. 29–35 (in Russian).
- Vekovshinina S.A., Kleyn S.V., Zhdanova-Zaplesvichko I.G., Chetverkina K.V. The quality of environment and risk to health of the population residing under the exposure to emissions from colored metallurgy enterprises and wood processing industry. Gigiena i sanitariya, 2018, vol. 97, no. 1, pp. 16–20. DOI: 10.18821/0016-9900-2018-97-1-16-20 (in Russian).
- Tokbergenov E.T., Dosmukhametov A.T., Askarov K.A., Amrin M.K., Askarov D.M., Beisenbinova Z.B. Assessment of aero-genic risks for people living in close proximity to Ulba metallurgical plant. Health Risk Analysis, 2022, no. 4, pp. 45–55. DOI: 10.21668/health.risk/2022.4.04.eng
- Abdolahnejad A., Jafari N., Mohammadi A., Miri M., Hajizadeh Y., Nikoonahad A. Cardiovascular, respiratory, and total mortality ascribed to PM10 and PM2.5 exposure in Isfahan, Iran. J. Educ. Health Promot., 2017, vol. 6, pp. 109. DOI: 10.4103/jehp.jehp_166_16
- Fattore E., Paiano V., Borgini A., Tittarelli A., Bertoldi M., Crosignani P., Fanelli R. Human health risk in relation to air quality in two municipalities in an industrialized area of Northern Italy. Environ. Res., 2011. vol. 111, no. 8, pp. 1321–1327. DOI: 10.1016/j.envres.2011.06.012
- Orru H., Maasikmets M., Lai T., Tamm T., Kaasik M., Kimmel V., Orru K., Merisalu E., Forsberg B. Health impacts of particulate matter in five major Estonian towns: Main sources of exposure and local differences. Air Qual. Atmos. Health, 2011, vol. 4, pp. 247–258. DOI: 10.1007/ s11869-010-0075-6