Assessment of carcinogenic risk caused by elevated 3,4-benz(a)pyrene concentration in soils in an industrial city

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UDC: 
614.7
DOI: 
10.21668/health.risk/2022.1.03.eng
Authors: 

L.А. Deryabkina1, B.I. Marchenko2, К.S. Tarasenko2

Organization: 

1Center for Hygiene and Epidemiology in Rostov Region, Taganrog Office, 16a Bol'shoi Ave., Taganrog, 347930, Russian Federation
2Southern Federal University, 105/42 Bol'shaya Sadovaya Str., Rostov-on-Don, 344006, Russian Federation

Abstract: 

Apparent destructive changes in soils typically occur in residential areas within urbanized ecological systems formed in large industrial cities. Elevated concentrations of super-toxicants and xenobiotics in soils, polycyclic aromatic hydrocarbons included, create high potential health risks for city population.

Our research goal was to assess the carcinogenic risk caused by elevated 3,4-benz(a)pyrene concentrations in soils in Taganrog, an industrial city with its population being about 250 thousand people located in Rostov region. The assessment included individual and population risks. There are two basic reasons which make the research vital. First of all, 3,4-benz(a)pyrene contents in soils in residential areas exceed hygienic standards. Secondly, the incidence of malignant neoplasms has been stably high in the city.

We analyzed the results of determining 3,4-benz(a)pyrene concentrations in 384 soil samples taken in 2013–2020 at 19 monitoring posts (located within residential areas close to crossroads with intense traffic, recreational zones, and areas around preschool children facilities). 3,4-benz(a)pyrene was established to be the priority pollutant in soils in the city with its share contribution to the complex pollution index (Csoil) being 55.25 %. 3,4-benz(a)pyrene concentrations were higher than maximum permissible ones in 65.63 % of all the examined soil samples; its average and maximum concentrations were equal to 2.298 and 45.525 MPC accordingly. We assessed the individual multi-route carcinogenic risk (CR) caused by elevated 3,4-benz(a)pyrene concentrations in soils. The risk turned out to be high (2.4606•10–3) and inhalation introduction was established as the priority one (94.84 %).

Keywords: 
social-hygienic monitoring, health risk, chemical soil pollution, 3,4-benz(a)pyrene, malignant neoplasms, carcinogenic risk assessment
Deryabkina L.А., Marchenko B.I., Tarasenko К.S. Assessment of carcinogenic risk caused by elevated 3,4-benz(a)pyrene concentration in soils in an industrial city. Health Risk Analysis, 2022, no. 1, pp. 27–35. DOI: 10.21668/health.risk/2022.1.03.eng
References: 
  1. Onishchenko G.G. Khimicheskaya bezopasnost' – vazhneishaya sostavlyayushchaya sanitarno-epidemiologicheskogo blagopoluchiya naseleniya [Chemical safety is the most important constituent of the sanitary and epidemiological well-being of population]. Toksikologicheskii vestnik, 2014, no. 1, pp. 2–6 (in Russian).
  2. Unguryanu T.N., Gudkov A.B., Nikanov A.N. Health risk assessment of soil contaminants for health of urban population. Profilakticheskaya i klinicheskaya meditsina, 2012, vol. 42, no. 1, pp. 101–105 (in Russian).
  3. Kryatov I.A., Tonkopiy N.I., Vodyanova M.A., Ushakova O.V., Doneryan L.G., Evseeva I.S., Matveeva I.S., Ushakov D.I. Scientific evidence for hygienic standards harmonized with international recommendations for priority polluitions of soils. Gigiena i sanitariya, 2015, vol. 94, no. 7, pp. 42–48 (in Russian).
  4. Unguryanu T.N., Novikov S.M. Approaches to assessing the health risk under exposure to chemicals with account of age peculiarities. Gigiena i sanitariya, 2012, vol. 91, no. 5, pp. 98–101 (in Russian).
  5. Boev V.M., Zelenina L.V., Kryazhev D.A., Tulina L.M., Neplokhov A.A. Analysis on exposure carcinogenic risk of environmental factors on health largest industrial cities and malignant tumors. ZNiSO, 2016, vol. 279, no. 6, pp. 4–7 (in Russian).
  6. Nielsen T., Jorgensen H.E., Larsen J.C., Poulsen M. City air pollution of polycyclic aromatic hydrocarbons and other mutagens: occurrence, sources and health effects. Sci. Total Environ., 1996, vol. 189–190, pp. 41–49. DOI: 10.1016/0048-9697(96)05189-3
  7. Rakhmanin Yu.A., Levanchuk A.V., Kopytenkova O.I. Improvement of the system of social and hygienic monitoring of territories of large cities. Gigiena i sanitariya, 2017, vol. 96, no. 4, pp. 298–301. DOI: 10.18821/0016-9900-2017-96-4-298-301 (in Russian).
  8. Butenko G.S., Polonskaya D.E. 3,4-benz(a)pyrene availability in the technogenically polluted territory soils. Vestnik KrasGAU, 2012, no. 7, pp. 86–90 (in Russian).
  9. Gabov D.N., Beznosikov V.A., Kondratenok B.M., Yakovleva E.V. Polycyclic aromatic hydrocarbons in the soils of technogenic landscapes. Geochemistry International, 2010, vol. 48, no. 6, pp. 569–579. DOI: 10.1134/S0016702910060042
  10. Benhaddya M., Boukhelkhal A., Halis Y., Hadjel M. Human health risks associated with metals from urban soil and road dust in an oilfield area of Southeastern Algeria. Arch. Environ. Contam. Toxicol., 2016, vol. 70, no. 3, pp. 556–571. DOI: 10.1007/s00244-015-0244-6
  11. Bispo A., Jourdain M.J., Jauzein M. Toxicity and genotoxicity of industrial soils polluted by polycyclic aromatic hydrocarbons (PAHs). Organic Geochemistry, 1999, vol. 30, no. 8B, pp. 947–952.
  12. Tsibart A.S., Gennadiev A.N. Polycyclic aromatic hydrocarbons in soils: sources, behavior, and indication significance (a review). Eurasian Soil Science, 2013, vol. 46, no. 7, pp. 728–741. DOI: 10.1134/S1064229313070090
  13. Nikiforova E.M., Alekseeva T.A. Polycyclic aromatic hydrocarbons in the soils of roadside ecosystems of Moscow. Eurasian soil science, 2002, vol. 35, no. 1, pp. 42–52.
  14. Sosa D., Hilber I., Faure R., Bartolome N., Fonseca O., Keller A., Bucheli T.D., Escobar A. Polycyclic aromatic hydrocarbons and polychlorinated biphenyls in urban and semi-urban soils of Havana, Cuba. Journal of soils and sediments, 2019, vol. 19, no. 3, pp. 1328–1341. DOI: 10.1007/s11368-018-2137-6
  15. Glaser B., Dreyer A., Bock M., Fielder S., Mehring M., Heitmann T. Source apportionment of organic pollutants of a highway-traffic-influenced urban area in Bayreuth (Germany) using biomarker and stable carbon isotope signatures. Environ. Sci. Technol., 2005, vol. 39, no. 11, pp. 3911–3917. DOI: 10.1021/es050002p
  16. Watts A., Ballestero T., Gardner K. Soil and atmospheric inputs to PAH concentrations in salt marsh plants. Water Air and Soil Pollution, 2008, vol. 189, no. 1, pp. 253–263. DOI: 10.1007/s11270-007-9572-0
  17. Gorobtsova O.N., Nazarenko O.G., Minkina T.M., Borisenko N.I. Soderzhanie 3,4-benz(a)pi¬rena v rastitel'nosti, raspolozhennoi v zone vliyaniya Novocherkasskoi GRES [Content of 3,4-benz(a)py¬rene in vegetation located in the zone influenced by the Novocherkassk hydro-recirculation power plant]. Izvestiya vysshikh uchebnykh zavedenii. Severo-Kavkazskii region. Seriya: Estestvennye nauki, 2006, no. 3, pp. 63–66 (in Russian).
  18. Baek S., Field R., Goldstone M., Kirk P., Lester J., Perry R. A review of atmospheric polycyclic aromatic hydrocarbons: sources, fate and behavior. Water, Air, and Soil Pollution, 1991, vol. 60, pp. 279–300.
  19. Gustafson P., Ostman C., Sallsten G. Indoor levels of polycyclic aromatic hydrocarbons in homes with or without wood burning for heating. Environ. Sci. Technol., 2008, vol. 42, no. 14, pp. 5074–5080. DOI: 10.1021/es800304y
  20. Barra R., Castillo C., Machado Torres J. Polycyclic aromatic hydrocarbons in the South American environment. Rev. Environ. Contam. Toxicol., 2007, vol. 191, pp. 1–22. DOI: 10.1007/978-0-387-69163-3_1
  21. Blomqvist P., Persson B., Simonson McNamee M. Fire emissions of organics into the atmosphere. Fire Technology, 2007, vol. 43, no. 3, pp. 213–231. DOI: 10.1007/s10694-007-0011-y
  22. Callen M.S., de la Cruz M.T., Lopez J.M., Murillo R., Navarro M., Mastral A. Long-range atmospheric transport and local pollution sources on PAH concentrations in a South European urban area. Fulfilling of the European directive. Water Air and Soil Pollution, 2008, vol. 190, no. 1–4, pp. 271–285. DOI: 10.1007/s11270-007-9599-2
  23. Dvorska A., Lammel G., Klanova J. Use of diagnostic ratios for studying source apportionment and reactivity of ambient polycyclic aromatic hydrocarbons over Central Europe. Atmospheric Environment, 2011, vol. 45, no. 2, pp. 420–427. DOI: 10.1016/j.atmosenv.2010.09.063
  24. Wilcke W. Global patterns of polycyclic aromatic hydrocarbons (PAHs) in soil. Geoderma, 2007, vol. 141, no. 3–4, pp. 157–166. DOI: 10.1016/j.geoderma.2007.07.007
  25. Yakovleva E.V., Beznosikov V.A., Kondratenok B.M., Gabov D.N., Vasilevich M.I. Bioakkumulyatsiya politsiklicheskikh aromaticheskikh uglevodorodov v sisteme pochvarastenie [Bioaccumulation of polycyclic aromatic hydrocarbons in the soil-plant system]. Agrokhimiya, 2008, no. 9, pp. 66–74 (in Russian).
  26. Yakovleva E.V., Beznosikov V.A., Kondratenok B.M., Gabov D.N. Bioaccumulation of polycyclic aromatic hydrocarbons in the soil-plant systems of the Northern-Taiga biocenoses. Eurasian Soil Science, 2012, vol. 45, no. 3, pp. 309–320. DOI: 10.1134/S1064229312030143
  27. Deryabin A.N., Unguryanu T.N. Assessment of biological pollution of soil in the Ark-hangelsk region. ZNiSO, 2017, no. 7 (292), pp. 18–21. DOI: 10.35627/2219-5238/2017-291-7-18-21 (in Russian).
  28. Vodianova M.A., Kriatov I.A., Donerian L.G., Evseeva I.S., Ushakov D.I., Sbitnev A.V. Ecological hygienic assessment of soils quality in urban areas. Gigiena i sanitariya, 2016, vol. 95, no. 10, pp. 913–916. DOI: 10.18821/0016-9900-2016-95-10-913-916 (in Russian).
  29. Aydinov G.T., Marchenko B.I., Kovalev E.V. Modern epidemiological features of cancer incidence of population of Rostov region. ZNiSO, 2017, vol. 296, no. 11, pp. 7–15. DOI: 10.35627/2219-5238/2017-296-11-7-15 (in Russian).
  30. Onishchenko G.G., Novikov S.M., Rakhmanin Yu.A., Avaliani S.L., Bushtueva K.A. Osnovy otsenki riska dlya zdorov'ya naseleniya pri vozdeistvii khimicheskikh veshchestv, zagryaznyayushchikh okruzhayushchuyu sredu [Basics of health risk assessment under exposure to chemicals which pollute the environment]. Moscow, NII ECh i GOS Publ., 2002, 408 p. (in Rus-sian).
  31. Popova A.Yu., Gurvich V.B., Kuzmin S.V., Mishina A.L., Yarushin S.V. Modern issues of the health risk assessment and management. Gigiena i sanitariya, 2017, vol. 96, no. 12, pp. 1125–1129. DOI: 10.18821/0016-9900-2017-96-12-1125-1129 (in Russian).
  32. Zaytseva N.V., Popova A.Yu., May I.V., Shur P.Z. Methods and technologies of health risk analysis in the system of state management under assurance of the sanitation and epidemiological welfare of population. Gigiena i sanitariya, 2015, vol. 94, no. 2, pp. 93–98 (in Russian).
  33. Kurchanov V.I., Lim T.Ye., Voyetsky I.A., Golovin S.A. The relevance of assessment of multicompartment carcinogenic risk to health from exposure to chemicals that pollute the environment. ZNiSO, 2015, vol. 268, no. 7, pp. 8–12 (in Russian).
Received: 
14.12.2021
Approved: 
21.02.2022
Accepted for publication: 
21.03.2022

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