Contemporary risk factors that cause disseminated lung diseases

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E.A. Borodulina, E.V. Yakovleva


Samara State Medical University, 89 Chapaevskaya Str., Samara, 443099, Russian Federation


As per data provided by Rosstat, in 2018 primary morbidity with respiratory diseases amounted to 35,982 per 100 thousand people; respiratory diseases account for more than 25% in the structure of overall population morbidity and they to a great extent depend on risk factors occurrence. Disseminated lung diseases are combined into one specific group among respiratory diseases as per x-ray evidence.
Our research goal was to review contemporary risk factors that cause disseminated lung diseases in order to apply them in diagnostics. We searched for scientific works that were relevant for our research in such databases as RSCI, CyberLeninka, Scopus, Web of Science, MedLine, and PubMed.
There are a lot of classifications for disseminated lung diseases based on morphologic substrate peculiarities, etiology and other signs; it proves the issue is truly complicated. Patients with disseminated damage to lungs have similar x-ray picture of the disease and results obtained via general clinical tests also have no pathognomonic peculiarities. Clinical experts usually divide disseminations into those with infectious genesis (tuberculosis, HIV-associated disseminations, and fungus diseases) and those with non-infectious genesis (tumor disseminations, interstitial lung diseases, lysosomal storage disorders, etc.). The review outlines factors that influence both occurrence and development of lung diseases accompanied with dissemination syndrome. The greatest attention is paid to socially significant diseases as risk factors that cause them can be detected by a doctor in a patient’s case history and applied for differential diagnostics. It is necessary to develop relevant prevention activities aimed at reducing risks of disseminated lung diseases as they will allow preventing morbidity and mortality among patients suffering from lung disseminations caused by correctable risk factors.

lung dissemination syndrome, risk factors, interstitial lung diseases, tuberculosis, pneumonia, HIV-infection, bronchiole-alveolar cancer, amyloidosis, pneumoconiosis
Borodulina E.A., Yakovleva E.V. Contemporary risk factors that cause disseminated lung diseases. Health Risk Analysis, 2020, no. 4, pp. 181–187. DOI: 10.21668/health.risk/2020.4.20.eng
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