Peculiarities of morbidity and assessment of occupational health risks for workers who contact aerosols of man-made mineral fibers
E.A. Hutsich, G.E. Kosiachenko, S.I. Sychik
Scientific Practical Centre of Hygiene, 8 Akademicheskaya Str., Minsk, 220012, Belarus
Our research focused on health of workers who had contacts with aerosols of man-made mineral fibers.
Our research goal was to determine peculiarities related to dynamics and structure of morbidity with temporary disability and to assess occupational health risks for workers who had contacts with aerosols of man-made mineral fibers.
The paper dwells on the results obtained via in-depth interpretation analysis of morbidity with temporary disability among workers who were permanently involved in manufacturing heat insulating boards from mineral wool (the test group); morbidity was analyzed over a 5-year period taking into account workers’ sex, age, and working experience. Occupational conditionality of morbidity was assessed via comparative analysis as the test group was compared with the conditional reference group (workers employed at a workshop where cell concrete blocks were manufactured), overall morbidity parameters taken for the whole country, and morbidity parameters taken for construction materials manufacturing. Risk was assessed via applying occupational risk index, calculated on the basis of relative risk and total coefficient of working conditions.
We detected that morbidity with temporary disability among workers from the test group was authentically higher than morbidity among workers from the conditional reference group, regarding both all disease categories, and respiratory organs diseases in particular. Relative risk and etiological fraction of morbidity caused by working conditions indicates that such conditions have direct influence on morbidity with respiratory organs diseases among workers from the test group. Occupational risk index characterizes occupational risk for workers from the test group as being moderate but still requiring specific activities aimed at reducing it, although there is no urgent necessity to perform them. Workers from the test group also tended to have lower “health index” than those form the conditional reference group.
Morbidity with temporary disability among workers from the test group was authentically lower than in the Republic of Belarus on average as well as than standard parameters fixed for construction materials manufacturing; but it was statistically significantly higher than both in the country on average and in the branch for respiratory organs diseases, musculoskeletal and connective tissue diseases; it was also statistically significantly higher than on average in the country for digestive organs diseases and diseases of skin and subcutaneous tissue.
- Wolf J., Prüss-Ustün A., Ivanov I., Mudgal S., Corvalán C., Bos R., Neira M. Preventing disease through a healthier and safer workplace. Geneva, World Health Organization Publ., 2018, 96 p.
- Ross C.S., Lockey J.E. Vrednoe vozdeistvie na zdorov'e iskusstvennykh volokon [Adverse effects produced on health by synthetic fibers]. Available at: http://base.safework.ru/iloenc?print&nd=857400205&spack=110LogLength=0 (06.08.2019) (in Russian).
- Kopytenkova O.I., Levanchuk A.V., Tursunov Z.Sh. Assessment of health damage due to exposure to mineral wool fine dusts. Kazanskii meditsinskii zhurnal, 2014, vol. 95, no. 4, pp. 570–574 (in Russian).
- Harrison P., Holmes P., Bevan R., Kamps K., Levy L., Greim H. Regulatory risk assessment approaches for synthetic mineral fibres. Regulatory Toxicology and Pharmacology, 2015, vol. 73, no. 1, pp. 425–441. DOI: 10.1016/j.yrtph.2015.07.029
- Kudo Y., Aizawa Y. Safety Evaluation of Rock Wool after Nasal Inhalation in Rats. Industrial Health, 2011, vol. 49, no. 1, pp. 47–55. DOI: 10.2486/indhealth.ms1146
- Wohlleben W., Waindok H., Daumann B., Werle K., Drum M., Egenolf H. Composition, Respirable Fraction and Dis-solution Rate of 24 Stone Wool MMVF with their Binder. Particle and Fibre Toxicology, 2017, vol. 14, no. 1, 29 p. DOI: 10.1186/s12989-017-0210-8
- Man-made Vitreous Fibres. World Health Organization. International agency for research on cancer. Lyon, IARC Press Publ., 2002, 430 p.
- Pohlabeln H., Jöckel K.H., Brüske-Hohlfeld I., Möhner M., Ahrens W., Bolm-Audorff U., Arhelger R., Römer W. [et al.]. Lung cancer and exposure to man-made vitreous fibers: results from a pooled case-control study in Germany. American Journal of Industrial Medicine, 2000, vol. 37, no. 5, pp. 469–477. DOI: 10.1002/(sici)1097-0274(200005)37:53.0.co;2-d
- Wardenbach Р., Rödelsperger К., Roller М., Muhle Н. Classification of man-made vitreous fibers: Comments on the revaluation by an IARC working group. Regulatory toxicology and pharmacology, 2005, vol. 43, no. 2, pp. 181–193. DOI: 10.1016/j.yrtph.2005.06.011
- Rödelsperger K., Jöckel K.H., Pohlabeln H., Römer W., Woitowitz H.J. Asbestos and man-made vitreous fibers as risk factors for diffuse malignant mesothelioma: results from a German hospital-based case-control study. American journal of industrial medicine, 2001, vol. 39, no. 3, pp. 262–275. DOI: 10.1002/1097-0274(200103)39:33.0.co;2-r
- Kashansky S.V. Mesothelioma in Russia: systematic review of 3576 published cases from occupational medicine viewpoint. Meditsina truda i promyshlennaya ekologiya, 2008, no. 3, pp. 15–21 (in Russian).
- Muzalevsky P.N., Shoikhet Ya.N, Lazarev A.F., Grigoruk O.G. Mesotelioma: prevalence and modified factors (Literature review). Sibirskii onkologicheskii zhurnal, 2007, no. 2, pp. 77–83 (in Russian).
- Varyvonchyk D.V. Epidemiology of malignant mesothelioma in Ukraine (2001–2011). Ukraїns'kii zhurnal z problem meditsini pratsі, 2012, vol. 33, no. 4, pp. 56–69.
- Kundiev Yu.I., Varivonchik D.V. Professional'nyi rak: zlokachestvennaya mezotelioma [Occupational cancer: malignant mesothelioma]. Kiev, VD Avitsena Publ., 2015, 192 p. (in Russian).
- Cavallo D., Campopiano A., Cardinali G., Casciardi S., De Simone P., Kovacs D., Perniconi B., Spagnoli G. [et al.]. Cytotoxic and oxidative effects induced by man-made vitreous fibers (MMVFs) in a human mesothelial cell line. Toxicology, 2004, vol. 201, no. 1–3, pp. 219–229. DOI: 10.1080/02786820500380198
- Staruchova M., Collins A.R. , Volkovova K., Mislanová C., Kovacikova Z., Tulinska J., Kocan A., Staruch L. [et al.]. Occupational exposure to mineral fibres. Biomarkers of oxidative damage and antioxidant defence and associations with DNA damage and repair. Mutagenesis, 2008, vol. 23, no. 4, pp. 249–260. DOI: 10.1093/mutage/gen004
- Fireman E. Man-made mineral fibers and interstitial lung diseases. Current Opinion in Pulmonary Medicine, 2014, vol. 20, no. 2, pp. 194–198. DOI: 10.1097/MCP.0000000000000035
- Mukhammadiyeva G.F., Bakirov A.B., Karimova L.K., Karimov D.O., Beigul N.A., Gimaeva Z.F. Risk factors and features of occupational diseases in workers engaged into artificial mineral fibers production. Meditsina truda i promyshlennaya ekologiya, 2018, no. 1, pp. 19–23 (in Russian).
- Mikulich I.V., Rakevich A.V., Kapustinskaya T.A., Biryuk T.I. Sostoyanie uslovii truda i professional'noi zabolevaemosti v Respublike Belarus' za 2017 g. [Working conditions and occupational morbidity in the Republic of Belarus in 2017]. Minsk, Respublikanskii tsentr gigieny, epidemiologii i obshchestvennogo zdorov'ya Publ., 2018, 11 p. (in Russian).
- Sorokin G.A. The age and work experience dynamics of indices of health of employees as criteria for comparison of occupational and non-occupational risks. Gigiena i sanitariya, 2016, vol. 95, no. 4, pp. 355–360 (in Russian).