Dynamics of incidence with malignant neoplasms in the thyroid gland among Chelyabinsk region population over 1998–2016: Clynic and epidemiological characteristics

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DOI: 
10.21668/health.risk/2019.2.07.eng
Authors: 

S.A. Shalaginov1, L.Yu.Krestinina1, A.S. Domozhirova2, S.B. Sergiyko3,4

Organization: 

1Urals Research Center for Radiation Medicine, 68A Vorovsky Str., Chelyabinsk, 454076, Russian Federation
2 Chelyabinsk Regional Clinical Center for Oncology and Nuclear Medicine, 42 Blyuhera Str., Chelyabinsk, 454076, Russian Federation
3 South-Ural State Medical University of the Ministry of Healthcare of the Russian Federation, 64 Vorovsky Str., Chelyabinsk, 454092, Russian Federation
4 City Clinical Hospital № 1, 16 Vorovsky Str., Chelyabinsk, 454048, Russian Federation

Abstract: 

The paper dwells on assessing dynamics of incidence with malignant neoplasms (MN) in the thyroid gland among Chelyabinsk region population over 1998–2016. Dynamics is taken in different age groups; incidence with different malignant neoplasms is characterized among men and women.

The authors took data from major medical and diagnostic institutions in Chelyabinsk region where information about patients suffering from malignant neoplasms in the thyroid gland could be accumulated. We detected 4,467 people with the primary diagnose confirmed with histological (93.2 %) and cytological (6.8 %) research.

We detected that primary incidence with malignant neoplasms in the thyroid gland tended to grow in Chelyabinsk region and it completely corresponded to the dynamics in the Russian Federation as a whole. This growth was mostly due to an increase in primary incidence among people aged 60 and older. The research revealed that papillary carcinoma is the most widely spread malignant neoplasm with 68.1 % cases in the overall structure of thyroid gland carcinoma in Chelyabinsk region. This malignant neoplasm tended to grow steadily from 64.2 % in the beginning of the observation period to 73.0 % at the end of it. But at the same time follicular carcinoma tended to decrease from 25.5 % to 18.2 % cases just as an aggregated share of other carcinoma types which were relatively rare. Average age of men at the moment malignant neoplasms in the thyroid gland were detected in them was lower than that of women; they were 49.6 ± 0.22 and 50.9 ± 0.9, p<0.001, respectively. The highest average age was detected for people with non-differentiated malignant neoplasms (66.9 ± 0.7); the lowest one, for people with follicular carcinoma (49.7 ± 0.1), p<0.001.

Keywords: 
thyroid gland, malignant neoplasm, dynamics of MN, Chelyabinsk region, population, age, incidence, structure
Shalaginov S.A., Krestinina L.Yu., Domozhirova A.S., Sergiyko S.B. Dynamics of incidence with malignant neoplasms in the thyroid gland among Chelyabinsk region population over 1998–2016: clinic and epidemiological characteristics. Health Risk Analysis, 2019, no. 2, pp. 64–73. DOI: 10.21668/health.risk/2019.2.07.eng
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Received: 
07.09.2018
Accepted: 
15.03.2019
Published: 
30.06.2019

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