Non-carcinogenic risk for children population health in kazan caused by food products and food raw materials contamination

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S.F. Fomina, N.V. Stepanova


Kazan Federal University, Fundamental Medicine and Biology Institute, 18 Kremlevskaya street, Kazan, 420008, Russian Federation


The paper dwells on results of assessing non-carcinogenic risk for children health in Kazan caused by consumption of food products contaminated with chemicals. Research was performed in two stages (2007–2010 and 2011–2014) on children aged 3–6. Actual nutrition of children was examined via questioning and timing-weighing techniques. Daily doses were calculated allow-ing for regional exposure parameters at median (Me) and 95-th percentile level. We detected high non-carcinogenic risk at 95-th percentile level for methyl-mercury (3.89 and 3.33 in both periods correspondingly); high and intolerable for As (10.67 in the first period). We determined organs and systems in a body which were under greatest toxic effects. Alerting level of non-carcinogenic risk for central nervous system (HI = 3.03) was detected in the first period at median level. In 2007–2010 we detected the following high non-carcinogenic risks at the 95-th percentile level of a danger coefficient for children: non-carcinogenic risk for central nervous system (HI = 12.20), hormonal system (HI=12.87), immune system (HI=11.72), and alerting risk for development (HI=4.03). In 2011–2014 the following systems were most prone to overall toxic impacts: central nervous system and development (HI = 4.02 and 3.98 correspondingly). Non-carcinogenic effects risk over 2007–2011 for hormonal system (64 %), central nervous system (79 %), and immune system (91 %) was caused mostly by food products contamination with As. As for 2011–2014, the greatest risk factor was Pb introduction, (46 %) for hormonal system, and (57 %) for central nervous system.

chemical contaminants, regional exposure factors, children, share contribution, non-carcinogenic risk, critical organs, critical systems in a body
Fomina S.F., Stepanova N.V. Non-carcinogenic risk for children population health in Kazan caused by food products and food raw materials contamination. Health Risk Analysis, 2017, no. 4, pp. 42–48. DOI: 10.21668/health.risk/2017.4.04.eng
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