Combined spine and pelvis injuries in children living in conditions of harmful impact of aluminium industry

View or download the full article: 
PDF icon health-risk-analysis-2016-3-2.pdf
UDC: 
616.711-053.2: 616.718.19-071
DOI: 
10.21668/health.risk/2016.3.02.eng
Authors: 

M.B. Negreyeva1, V.S. Kopylov1, V.S. Ulyanov2

Organization: 

1 FSBSI “Irkutsk Scientific Center of Surgery and Traumatology”, 1 B. Revoljucii, Irkutsk, 664003, Russian Federation
2 FSFEI HE “Irkutsk State University”, 20 bul'var Gagarina, Irkutsk, 664003, Russian Federation

Abstract: 

The orthopedic and x-ray studies of children of different ages with combined diseases of the spine and pelvis, living under constant effects of the harmful production factors induced by the aluminium production of Irkutsk region, have been conducted. The priority factor of exogenous risk to health is fluoride compounds. It has been established that in the structure of the combined pathology, the pelvis asymmetry ranks first, scoliosis ranks second, Legg – Calve – Perthes disease ranks third. According to the assessment of age structure of combined pathology we can conclude that at the equal manifestations of scoliosis, Spina bifida, retrospondylolisthesis, pelvis asymmetry, children of 11–15 y.o. more often have Legg – Calve – Perthes disease, children of 16–21 y.o. – coxarthrosis. We established statistically significant correlation between Legg – Calve – Perthes disease and age and sex of the children (Pearson's χ 2 at p < 0.01 makes 15.821 and 21.228 correspondingly). It’s important to mention that Legg – Calve – Perthes disease was registered in all examined boys and only in 35.5 % of girls. Correlation between this pathology and ecological factors was also statistically proved (χ 2 = 5.264, p < 0.05): within the radius of 5 km from the production facility the proportion of avascular necrosis was the highest (75 % cases). I and II degrees of manifestation of clinicoroentgenologic disorders of combined spine and pelvis pathology prevail. The relevance of further search for evidence of the relationship of chemical risk factors and the development of diseases of the musculoskeletal system was determined. Regular medical follow-up monitoring of children living in ecologically unfavorable territories in terms of early diagnosis of combined orthopedic pathology is recommended, including its premorbid period of development.

Keywords: 
ecology, harmful production factors of aluminum production, combined spine and pelvis pathology, Legg – Calve – Perthes disease, children, age, sex
Negreyeva M.B., Kopylov V.S., Ulyanov V.S. Combined spine and pelvis injuries in children living in conditions of harmful impact of aluminium industry. Health Risk Analysis. 2016, no. 3, pp. 13–22. DOI: 10.21668/health.risk/2016.3.02.eng
References: 
  1. Antonov K.L., Varaksin A.N., Chukanov V.N. Vliyanie vybrosov na zdorov'e detej promyshlennogo centra [The outburst influence on the children's health living in the industrial center]. Jekologicheskie sistemy i pribory, 2005, no. 7, pp. 27–32 (in Russian).
  2. Negreeva M.B., Larionov S.N., Sorokovikov V.A., Shenderov V.A. Biomehanicheskie aspekty issledovanij degenerativno-distroficheskih zabolevanij pojasnichnogo otdela pozvonochnika i tazobedrennyh sustavov (obzor literatury) [Biomechanical aspects of researches of degenerative-dystrophic diseases of lumbar segment of spine and hip joints (the review of literature)]. Bjulleten' VSNC SO RAMN, 2013, vol. 93, no. 5, pp. 187–191 (in Russian).
  3. Vozrastnaja periodizacija [Age periodization]. Available at: https://ru.wikipedia.org/wiki/ Возрастная пе-риодизация (31.07.2015) (in Russian).
  4. Kuznecov S.B., Mikhailovskiy M.B., Sadovoj M.A., Korel' A.V., Mamonova E.V. Geneticheskie markery idiopaticheskogo i vrozhdjonnogo skoliozov i diagnoz predraspolozhennosti k zabolevaniju: obzor literatury [Ge-netic markers of idiopathic and congenital scoliosis, and diagnosis of susceptibility to the disease: review of the literature]. Hirurgija pozvonochnika, 2015, vol. 12, no. 1, pp. 27–35 (in Russian).
  5. Donskih I.V. Vlijanie ftora i ego soedinenij na zdorov'e naselenija (obzor dannyh literatury) [The influence of fluorine and its compounds on people's health (literature review)]. Bjulleten' VSNC SO RAMN, 2013, vol. 91, no. 3–2, pp. 179–185 (in Russian).
  6. Kalinina O.L. Ocenka sostojanija zdorov'ja rabotajushhih pri vozdejstvii ftorsoderzhashhih soedinenij v sovremennom proizvodstve aljuminija: avtoref. dis. … kand. med. nauk: 14.02.04 [Health assessment in workers exposed to fluorine-containing compounds in the modern aluminum production: abstract of thesis … Cand. of Medicine: 02.14.04]. Irkutsk, 2013, 21 p. (in Russian).
  7. Kopylov V.S., Kuvina V.N. Ortopedicheskaja patologija u detej i podrostkov v gorode s krupnym pro-myshlennym proizvodstvom [Orthopedic pathology in children and adolescents in the city of major industrial pro-duction]. Zdorov'e. Medicinskaja jekologija. Nauka, 2014, vol. 56, no. 2, pp. 108–109 (in Russian).
  8. Kuvina V.N., Kuvin S.S. Jekogennaja ortopedicheskaja patologija [Ecogenic orthopedic pathology]. Novosibirsk: Nauka; Irkutsk: NC RVH SO RAMN, 2013, 260 p. (in Russian).
  9. Makosko A.A., Matesheva A.V. O tendencijah rasprostranjonnosti jekologicheski obuslovlennyh zabolevanij vsledstvie tehnogennogo zagrjaznenija atmosfery [Prevalence trends of environment-related diseases due to the anthropogenic air pollution]. Innovacii, 2012, vol. 168, no. 10, pp. 98–105 (in Russian).
  10. Negreeva M.B., Sorokovikov V.A. Kompleksnyj podhod k lecheniju bol'nyh osteoartrozom [Comprehen-sive approach to the treatment of patients with osteoarthritis]. Materialy III S’ezda travmatologov-ortopedov Sibirskogo federal'nogo okruga. In: d.m.n. V.A. Peleganchuka, d.m.n., professora M.A. Sadovogo, eds. (otv. re-daktor chl. SP RF V.V. Shalygin), 2014, pp. 233–238 (in Russian).
  11. Orel A.M. Vozrastnye aspekty jepidemiologii degenerativno-distroficheskih izmenenij mezhpozvonkovyh diskov po dannym sistemnogo analiza rentgenogramm pozvonochnika [Age Aspects Epidemiology of Degenerative Dystrophic Changes Intervertebral Disks on Data System Analysis Spine Roentgenograms]. Medicinskaja vizualizacija, 2010, no. 5, pp. 113–121 (in Russian).
  12. Luzhetskiy K.P., Ustinova O.Ju., Maklakova O.A., Palagina L.N. Osobennosti jendokrinnyh narushenij u detej, prozhivajushhih v uslovijah v uslovijah vysokogo riska ingaljacionnogo vozdejstvija benzola, fenola i bez(a)pirena [Characteristics of endocrine disorders in children, living in conditions of high level risk of inhalation exposure to benzene, phenol, benzo(a)pyrene]. Analiz riskov zdorov'ju, 2014, no. 2, pp. 97–103 (in Russian).
  13. Gurvich V.B., Kuz'min S.V., Plotko Je.G., Seljankina K.P., Privalova L.I., Vinokurov M.V., Ryzhov V.V., Voronin S.A., Vinokurova M.V. Ocenka mnogosredovogo riska – osnova upravlenija zdorov'em naselenija v rajonah razmeshhenija aljuminievyh proizvodstv [Evaluation of multimedia risk – the basis of public health man-agement in the areas with aluminum production]. Materialy pervoj mezhdunarodnoj konferencii seti vsemirnoj organizacii zdravoohranenija stran vostochnoj Evropy po problemam kompleksnogo upravlenija zdorov'em rabotajushhih, 23–25 September 2003. Ufa, 2003, pp. 207–210 (in Russian).
  14. Rukovodstvo po ocenke riska dlja zdorov'ja naselenija pri vozdejstvii himicheskih veshhestv, zagrjazn-jajushhih okruzhajushhuju sredu R.2.1.10.1920–04 [Guidelines for assessing health risk in the popula-tion exposed to the chemicals polluting the environment R.2.1.10.1920–04]. Moscow: Federal'nyj centr Gossan-jepidnadzora Minzdrava Rossii, 2004, 143 p. Available at: http://www.znaytovar.ru/gost/2/r_2110192004_ruko-vodstvo_po_oc.htm/ (05.08.2016) (in Russian).
  15. Seliverstov P.V. Rol' sovremennyh metodov vizualizacii v diagnostike zabolevanij tazovogo pojasa u de-tej [The role of modern methods of visualization in diagnostics of the diseases of pelvic zone in children]. Sibirskij medicinskij zhurnal, 2006, no. 9, pp. 90–93 (in Russian).
  16. Sirina N.V. Ocenka zagrjaznenija atmosfernogo vozduha predprijatijami aljuminievoj promyshlenosti Ir-kutskoj oblasti: avtoref. dis. … kand. med. nauk: 25.00.36 [Evaluation of air pollution aluminum industry of the Irkutsk Region:: abstract of thesis … Cand. of Medicine: 25.00.36]. Habarovsk, 2009, 21 p. (in Russian).
  17. Hominec V.V., Kudjashev A.L., Shapovalov V.M., Miroevskij F.V. Sovremennye podhody k diagnostike sochetannoj degenerativno-distroficheskoj patologii tazobedrennogo sustava i pozvonochnika [Modern approaches to diagnostics of combined degenerative hip and spine pathology]. Travmatologija i ortopedija Rossii, 2014, no. 4, pp. 16–25 (in Russian).
  18. Syurin S.A. Sostojanie zdorov'ja rabotnikov aljuminievoj promyshlenosti evropejskogo severa Rossii [Health state of aluminum industry workers in the European North of Russia]. Gigiena i sanitarija, 2015, vol. 94, no. 1, pp. 68–72 (in Russian).
  19. Ul'rih Je.V., Mushkin A.Ju. Hirurgicheskoe lechenie porokov razvitija pozvonochnika u detej [Surgical treatment of spinal malformations in children]. St.Petersburg: JeLBI-SPb, 2007, 104 p. (in Russian).
  20. Chubirko M.I., Pichuzhkina N.M., Masajlova L.A. Zagryaznenie atmosfernogo vozduha – faktor riska zdorov'ja detskogo naselenija [Air pollution is a risk factor for children''s health]. Sovremennaja medicina: ak-tual'nye voprosy, 2014, no. 31, pp. 78–82 (in Russian).
  21. Shalina T.I. Zagryaznenie okruzhajushhej sredy ftoristymi soedinenijami aljuminievogo proizvodstva i ih vlijanie na morfogenez kostej: avtoref. dis. … dokt. med. nauk: 14.00.07, 14.00.02 [Pollution with aluminum fluo-ride production and its impact on bone morphogenesis: abstract of thesis … Doctor of Medicine: 14.00.07, 14.00.02]. Irkutsk, 2009, 52 p. (in Russian).
  22. Shalina T.I., Vasil'eva L.S. Analiz obshhej zabolevaemosti detej i podrostkov po klassam boleznej v pro-myshlennyh gorodah [The analysis of general diseases in children and adolescents of the industrial cities]. Sibirskij medicinskij zhurnal, 2009, vol. 85, no. 2, pp. 66–68 (in Russian).
  23. Shalina T.I., Vasil'eva L.S. Vlijanie soedinenij ftora na morfogenez bedrennyh kostej plodov cheloveka [The influence of fluoride on the femoral bones morphogenesis of the human fetus]. Sibirskij medicinskij zhurnal, 2009, vol. 84, no. 1, pp. 42–46 (in Russian).
  24. Chen F, Shen JX, Qiu GX. Features of pelvic parameters in adolescent idiopathic scoliosis and their rela-tionships with spinal sagittal parameters. Zhonghua Yi Xue Za Zhi, 2013, vol. 93, no. 7, pp. 487–90. Chinese.
  25. Negreeva M.B., Seliverstov P.V. Development of a database of children and adolescents with concomitant orthopedic pathology for diagnostic decision support solutions and prognosis of the disease. II international congress of the countries the Shanghai cooperation organization “Traumatology, orthopedy and regenerative medicine of the third millennium”, Manchzhouli Citi (China), may, 26–29 th, 2016, pp. 100–102.
  26. Berjano P., Langella F., Ismael M.F., Damilano M., Scopetta S., Lamartina C. Successful correction of sagittal imbalance can be calculated on the basis of pelvic incidence and age. Eur Spine J., 2014 Oct; 23, no. 6, pp. 587–596.

You are here

Home