Interaction between risk factors of premorbid pathologies and dysfunction predictors of endothelial of a locomotive depot’s group of workers

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DOI: 
10.21668/health.risk/2015.4.09.eng
Authors: 

N.N. Malyutina, L.A. Taranenko, A.S. Tolkach, M.S. Nevzorova

Organization: 

SBEI HPE “Perm State Medical University named after E.A.Wagner” of Ministry of Health of Russian Federation, Russian Federation, Perm, 26 Petropavlovskaya St., 614990

Abstract: 

The article proved a stable connection between an essential hypertension (EH) development, life-threatening arrhythmias and conduction under the impact of a complex of occupational factors, first of all psycho-emotional stress, noise and electromagnetic radiation. We analyzed the initial manifestations of endothelial dysfunction of the locomotive engine drivers. We found an increase of the performance of endothelin-1 (1.59 ± 0.29 p/mole/ ml), MCP-1 (268.83 ± 23.29 pg/ml). Revealed changes are proposed as laboratory predictors and forecast criteria of initial lesion of the vascular bed.

Keywords: 
illness, work-related, endothelial dysfunction, hypertension, arrhythmias and conductibility
Malyutina N.N., Taranenko L.A. , Tolkach A.S., Nevzorova M.S. Interaction between risk factors of premorbid pathologies and dysfunction predictors of endothelial of a locomotive depot’s group of workers. Health Risk Analysis, 2015, no. 4, pp. 73-78
References: 
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