Characteristics of endocrine disorders in children, living in conditions of high level risk of inhalation exposure to benzene, phenol, benzo(a) pyrene

View or download the full article: 
PDF icon health-risk-analysis-2014-2-12.pdf
UDC: 
616-008
DOI: 
10.21668/health.risk/2014.2.12.eng
Authors: 

K.P. Luzhetsky1,2, O.Yu. Ustinova1,2, O.A. Maklakova1,2, L.N. Palagina1

Organization: 

1 FBSI “Federal Scientific Center for Medical and Preventive Health Risk Management Technologies”, Russian Federation, Perm, 82 Monastyrskaya St., 614045
2 Perm State National Research University, Russian Federation, Perm, 15 Bukireva St., 614990

Abstract: 

The study of incidence of endocrine diseases in children, living in conditions of high level risk of inhalation exposure to chemical technogenic factors of large industrial center, has been performed. In the condition of high level risk of chronic aerogenic exposure to benzene, phenol, benzo (a) pyrene the violations of thyroid homeostasis, carbohydrate and fat metabolism (goiter (E04.9), the excess food (E67.8) and obesity (E66.0)) were diagnosed in 1.3-2.0 times more likely than in the comparison group. The relationship of the formation of endocrine disorders in children with increased content of benzene, phenol and benzo (a) pyrene in blood has been established. Children, living in the areas with chemical atmospheric pollution with substances influencing hormonogenesis and light iodine deficit, have a reduced level of iodine provision, changes in the structure and volume of the thyroid gland 1.7-2.4 times higher than in the comparison group.

Keywords: 
children, endocrine disorders, benzene, phenol, benzo (a) pyrene
Luzhetsky K.P., Ustinova O.Yu., Maklakova O.A., Palagina L.N. Characteristics of endocrine disorders in children, living in conditions of high level risk of inhalation exposure to benzene, phenol, benzo(a) pyrene. Health Risk Analysis, 2014, no. 2, pp. 97-103
References: 
  1. Baranov A.A., Il'in A.G. Osnovnye tendencii dinamiki sostojanija zdorov'ja detej v rossijskoj federacii. puti reshenija problem [Key trends in the health of children in the Russian Federation. Solutions to the problems]. Vestnik Rossijskoj akademii medicinskih nauk, 2011, no. 6, pp. 12–18.
  2. Vozgoment O.V., Korjukina I.P., Aminova A.I., Luzheckij K.P., Farnosova S.V. Gigienicheskaja harakter-istika faktorov, formirujushhih tireoidnuju patologiju u detej [Hygienic characteristics of the factors forming the thyroid pathology in children]. Fundamental'nye issledovanija, 2010, no. 2, pp. 28–30.
  3. Dedov I.I., Mel'nichenko G.A., Troshina E.A. Deficit joda – ugroza zdorov'ju i razvitiju detej v Rossii. (Nacional'ny doklad) [Iodine deficiency - a threat to the health and development of children in Russia. (National report)]. Moscow, 2006. 123 p.
  4. Zajceva N.V., Zemljanova M.A., Kir'janov D.A. Vyjavlenie osobennostej formirovanija joddeficitnyh sostojanij u detej v uslovijah vozdejstvija jekologicheskih faktorov maloj intensivnosti (na primere Permskoj oblasti) [Identifying the features of formation of iodine deficiency states in children under the impact of environmental factors of low intensity (on the example of the Perm region)]. Vestnik Rossijskoj akademii medicinskih nauk, 2001, no. 6, pp. 39.
  5. Zajceva N.V., Maj I.V., Balashov S.Ju. Mediko-biologicheskie pokazateli sostojanija zdorov'ja naselenija v uslovijah kompleksnogo prirodno-tehnogennogo zagrjaznenija sredy obitanija [Biomedical public health indicators in the conditions of integrated natural and man-made environmental pollution]. Izvestija Samarskogo nauchnogo centra Rossijskoj akademii nauk, 2009, vol. 11, no. 1–6, pp. 1144–1148.
  6. Luzheckij K.P., Ustinova O.Ju., Palagina L.N. Strukturno-dinamicheskij analiz jendokrinnoj patologii u detej, prozhivajushhih v uslovijah vozdejstvija himicheskih tehnogennyh faktorov sredy obitanija (na primere Permskogo kraja) [Structural and dynamic analysis of endocrine diseases in children living in the conditions of chemical man-made environmental factors (on the example of the Perm Krai)]. Zdorov'e naselenija i sreda obi-tanija, 2013, no. 11 (248), pp. 32–35.
  7. Luzheckij K.P. Joddeficitnye zabolevanija prirodno-obuslovlennogo proishozhdenija u detej Permskogo kraja [Iodine deficiency diseases of natural origin in children of the Perm Krai]. Zdorov'e naselenija i sreda obi-tanija: ezhemesjachnyj informacionnyj bjulleten', Moscow, 2010, no. 3, pp. 25–30.
  8. Luzheckij K.P., Korjukina I.P., Ustitnova O.Ju., Burdina L.V., Shtina I.E. Osobennosti kliniko-laboratornogo statusa u detej s joddeficitnymi zabolevanijami, prozhivajushhih v uslovijah kombinirovannogo voz-dejstvija prirodno-tehnogennyh faktorov [Peculiarities of clinical and laboratory status in children with iodine deficiency diseases, living in the combined effects of natural and man-made factors]. Fundamental'nye issledo-vanija, 2010, no. 2, pp. 65–67.

You are here

Home