Post-vaccination immunity against diphtheria, measles, tetanus and pertussis in children exposed to environmental chemical factors

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UDC: 
61.616.9
DOI: 
10.21668/health.risk/2013.2.03.eng
Authors: 

O.Yu. Ustinova, V.G. Makarova, O.V. Dolgikh

Organization: 

Federal Budget Scientific Institution “Federal Scientific Center for Medical and Preventive Health Risk Management Technologies”, Russian Federation, Perm, 82 Monastyrskaya St, 614045

Abstract: 

An assessment of post-vaccination immunity against diphtheria, measles, tetanus and pertussis in children with increased levels of chemical toxicants, caused by environmental exposure was conducted. It was determined that the levels of post-vaccination antibodies in this group of children were significantly lower than those in children living in environmentally favorable areas and that disorders in the development of post-vaccination immunity were observed 1.5 to 2.4 times more often. A true relationship between a decrease in the levels of specific post-vaccination antibodies and an increase in the levels of lead, chromium, manganese and o-cresol in the blood was identified.

Keywords: 
children, post-vaccination immunity, diphtheria, pertussis, measles, tetanus, environmental exposure, chemical factors
Ustinova O.Yu., Makarova V.G., Dolgikh O.V. Post-vaccination immunity against diphtheria, measles, tetanus and pertussis in children exposed to environmental chemical factors. Health Risk Analysis, 2013, no. 2, pp. 27-38
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